Benchtop Headspace Gas Analyzer

Lasercube is a benchtop instrument conceived for performing the Headspace Gas Analysis (HGA) of sterile pharmaceutical containers. Fully automated test cycle sequencing with manual loading and unloading of containers.


  • Double path system
  • Nitrogen purging not required
  • Automatic height adjustment
  • HMI real-time display of statistics and raw data

Tech Specification and Features

Technical Features

  • Container Application: Ampoules, Vials, Cartridges, Pre-filled Syringes
  • Products: Freeze dried, Liquid, Powder
  • Container Dimensions: Ø [10 - 69] mm
  • Speed: 4 cpm (max)
  • Technology: Tunable Diode Laser Absorption Spectroscopy (TDLAS)
  • Inspection Features: Non-intrusive, non-destructive, laser-based inspection method
  • Inspection Capabilities: Oxygen/Moisture/Carbon Dioxide level, Absolute Pressure value

Additional Features

  • Etalon effect negligible
  • No reference container required
  • Extreme stability and accuracy even with limited headspace
  • Automatic spinning plate for complete container rotation
  • Lightweight
  • Fast, reliable and repeatable results
  • Cost-effective solution with low power consumption


  • HGA inspection process based on Tunable Diode Laser Absorption Spectroscopy (TDLAS) method to accurately quantify gaseous concentration levels.
  • Diode laser beam transmitted through headspace region of the container and reflected back towards the receiver.
  • Lasercube sensors measure the laser beam absorption related to target gas concentration.

Quality Assurance

  • Software designed to comply with FDA 21 CFR Part 11 and EU Annex 11
  • Testing method in conformity with provisions of USP - United States Pharmacopeia - General Chapter <1207>
  • Standard containers set supplied for easy calibration and verification
  • Easy to perform validations and qualifications thanks to advanced protocols and documentation